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AB9358 Anti-Neuropeptide Y2 Receptor Antibody

This Anti-Neuropeptide Y2 Receptor Antibody is validated for use in IH for the detection of Neuropeptide Y2 Receptor.

Anti-Neuropeptide Y2 Receptor Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: CNS Control of Metabolism, Hormones & Receptors Gene Symbol: NPY2R, NPY2-R UniProt Number: P49146
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AB9358
50 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RIHCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB9358
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Neuropeptide Y2 Receptor Antibody
      References
      Product Information
      FormatSerum
      PresentationAffinity purified immunoglobulin. Liquid in PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Neuropeptide Y2 Receptor Antibody is validated for use in IH for the detection of Neuropeptide Y2 Receptor.
      Key Applications
      • Immunohistochemistry
      Application NotesImmunohistochemistry: 1:500-1:1,000 (see application notes that follow).

      Optimal working dilutions must be determined by the end user.

      APPLICATION NOTES FOR AB9358

      IMMUNOHISTOCHEMISTRY

      Suggested perfusion: 1) Ca2+-free Tyrode's solution followed by 2) paraformaldehyde-picric acid fixative, and 3) 10% sucrose in PBS as a cryo-protectant. Tissues were rapidly dissected out and stored overnight in 0.1 M phosphate buffer (pH 7.4) containing 10% sucrose. Slide-mounted tissue sections were incubated with blocking buffer for 1 hour at room temperature. Primary antibody was diluted in blocking buffer to the appropriate working dilution. Blocking buffer was removed and the slides were then incubated at 2-8°C for 18-24 hours with AB9358. After rinsing in PBS 3 times sections were incubated for 60 minutes at room temperature with fluorescently labeled secondary antibody.
      Biological Information
      ImmunogenSynthetic peptide from Neuropeptide Y2 Receptor.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Neuropeptide Y2 Receptor.
      Species Reactivity
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NPY2R
      • NPY2-R
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P49146 # Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
      SIZE: 381 amino acids; 42731 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.
      SIMILARITY: SwissProt: P49146 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9358 04053252334887