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AB5888 Anti-NOGO A Antibody

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AB5888
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, H, RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB5888
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-NOGO A Antibody
      Alternate Names
      • Neurite outgrowth inihibitor A
      Background InformationThis gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified
      References
      Product Information
      FormatAffinity Purified
      Control
      • mouse brain lysate
      PresentationPurified in PBS with 0.05% NaN3
      Quality LevelMQ100
      Applications
      ApplicationAnti-NOGO A Antibody detects level of NOGO A & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesOptimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic Linear Peptide
      EpitopeUnknown
      HostRabbit
      SpecificityCat. # AB5888 is specific to NOGO A. It does not recognize NOGO B or NOGO C.
      Species Reactivity
      • Mouse
      • Human
      • Rat
      Species Reactivity NoteMouse, Human and Rat. Reactivity with other species has not been tested.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      UniProt Number
      Molecular WeightTheoretical MW is approx. 126 kDa however literature reports observed molecular weight to be 205 kDa to 220 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely tested on mouse brain lysate
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB5888 04053252618680

      Documentation

      Anti-NOGO A Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-NOGO A Antibody Certificates of Analysis

      TitleLot Number
      Anti-NOGO A 2484197
      Anti-NOGO A - 2066696 2066696
      Anti-NOGO A - 2186327 2186327
      Anti-NOGO A - 2228095 2228095
      Anti-NOGO A - 2283373 2283373
      Anti-NOGO A - 2365535 2365535
      Anti-NOGO A - 3026947 3026947
      Anti-NOGO A - 3170216 3170216
      Anti-NOGO A - 3891824 3891824
      Anti-NOGO A - LV1714995 LV1714995

      References

      Reference overviewPub Med ID
      Soluble Nogo-A, an inhibitor of axonal regeneration, as a biomarker for multiple sclerosis.
      Anna Jurewicz,Mariola Matysiak,Cedric S Raine,Krzysztof Selmaj
      Neurology  68  2007

      Show Abstract
      17242333 17242333