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ABN354 Anti-NIPSNAP2 Antibody

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ABN354
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN354
      DescriptionAnti-NIPSNAP2 Antibody
      Alternate Names
      • Non-neuronal SNAP25-like protein 2
      • Glioblastoma-amplified sequence
      • GBAS
      Background InformationThe NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human skeletal muscle tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect the NIPSNAP2 protein using this Anti-NIPSNAP2 validated for use in WB & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 2.5µg/mL of this antibody from a representative lot detected NIPSNAP2 in mouse skeletal muscle tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human NIPSNAP2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityNIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • GBAS
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~31 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human skeletal muscle tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected NIPSNAP2 in 15 µg of human skeletal muscle tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN354 04053252847615