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ABF108 Anti-IL-33 Antibody

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ABF108
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, FCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABF108
      DescriptionAnti-IL-33 Antibody
      Alternate Names
      • Interleukin-33
      • IL-33
      • Interleukin-33(102-266)
      • Interleukin-33(109-266)
      Background InformationIL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, leading to the activation of MAP kinases and NF-kappaB. IL-33 induces production of helper T-cell type 2 (TH2) cytokines, including IL-4, IL-5 and IL-13, and is a known mediator of many inflammation responses. Cat. No. ABF108, Anti-IL-33, is an affinity purified rabbit polyclonal antibody that recognizes epitopes in the C-terminal half of murine IL-33. Reactivity to rat or other species has not been tested.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-IL-33 Antibody is an antibody against IL-33 for use in Western Blotting, Flow Cytometry.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: 0.25 µg of this antibody from a representative lot detected IL-33 in 1X10E6 monensin treated MEF1 cells.
      Biological Information
      ImmunogenHis-tagged recombinant protein corresponding to the C-Terminal of mouse IL-33.
      EpitopeC-Terminal
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Il33
      Purification MethodAffinity
      UniProt Number
      Molecular Weight~35 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in MEF1 cell lysate.

      Western Blotting Analysis: 0.1 µg/mL of this antibody detected IL-33 in 10 µg of MEF1 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABF108 04055977163971