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ABN1347-25UL Anti-Glutathione S-transferase A5 (GSTA5)

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ABN1347-25UL
25 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN1347-25UL
      DescriptionAnti-Glutathione S-transferase A5 (GSTA5)
      Alternate Names
      • EC:2.5.1.18
      • GST class-alpha member 5
      • Glutathione S-transferase A5-5
      • Glutathione S-transferase alpha 5
      Background InformationGlutathione S-transferase A5 (UniProt: Q7RTV2; also known as EC: 2.5.1.18, GST class-alpha member 5, Glutathione S-transferase A5-5) is encoded by the GSTA5 gene (Gene ID: 221357) in human. Glutathione S-transferases are soluble proteins that catalyze the conjugation of reduced glutathione and a variety of electrophiles, including many known carcinogens and mutagens. Glutathione S-transferase A5 is a homodimeric cytoplasmic protein with two glutathione binding sites. The mammalian glutathione S-transferases are active in drug metabolism are classified into the alpha, mu and pi classes. Members of the alpha-class of glutathione S-transferases show substrate specificity for cumene hydroperoxide (CuOOH) and 7-chloro-4-nitrobenz-2-oxa-1, 3-diazole (NBD-C1). They exhibit a number of differences from the characteristic glutathione S-transferase structure. For example, in its domain II, it contains a short 3-residue beta-strand near the C-terminal segment and a longer alpha-7 helix.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationAnti-Glutathione S-transferase A5 (GSTA5) Antibody, Cat. No. ABN1347, is a highly specific rabbit polyclonal antibody that detects human Glutathione S-transferase A5 and has been tested in Immunohistochemistry (Paraffin) and Western Blotting.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry (Paraffin) Analysis (IHC(P)): A 1:250 Dilution of this antibody detected Glutathione S-transferase A5 in human liver.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to 14 amino acids from the internal region of human Glutathione S-transferase A5.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThis rabbit polyclonal antibody detects Glutathione S-transferase A5 in Human Liver. It targets an epitope within 14 amino acids from the internal region.
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Monkey based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • GSTA5
      Purification MethodAffinity Purified
      UniProt Number
      Molecular Weight25 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Human Liver.
      Western Blotting Analysis (WB): A 1:2000 Dilution of this antibody detected Glutathione S-transferase A5 in Human Liver.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size25 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN1347-25UL 04054839480188