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MABF271 Anti-FPR1/2 Antibody, clone NFPR1

Anti-FPR1/2 Antibody, clone NFPR1 is an antibody against FPR1/2 for use in Western Blotting, Flow Cytometry, Immunocytochemistry, Immunoprecipitation.

Anti-FPR1/2 Antibody, clone NFPR1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: FPR1 UniProt Number: P21462
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MABF271
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, FC, ICC, IPMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABF271
      DescriptionAnti-FPR1/2 Antibody, clone NFPR1
      Alternate Names
      • Anti-Formyl Peptide Receptor 1/2
      • FMLP1/2
      • fMet-Leu-Phe receptor
      • fMLP receptor
      • N-formyl peptide receptor
      • FPR
      • N-formylpeptide chemoattractant receptor
      Background InformationN-formy peptide receptor 1 (also known as N-formylpeptide chemoattractant receptor or fMet-Leu-Phe receptor) & 2 (also known as RFP, FMLP-R-I, Lipoxin A4 receptor, LXA4 receptor, FMLP-related receptor I, Formyl peptide receptor-like 1) are multi-pass cell membrane G protein-coupled receptors (GPCRs) encoded by the FPR1 (also known as FPR and FMLP) and FPR2 (also known as FPR2 and FMLP-R-II) gene in human, respectively. The FPR1 gene encodes the high-affinity, and FPR2 the low-affinity, receptor for N-formyl-methionyl peptides (FMLP). Both receptors mediate FMLP-induced activation of neutrophils.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-FPR1/2 Antibody, clone NFPR1 is an antibody against FPR1/2 for use in Western Blotting, Flow Cytometry, Immunocytochemistry, Immunoprecipitation.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      • Immunocytochemistry
      • Immunoprecipitation
      Application NotesFlow Cytometry Analysis: A representative lot detected FPR1/2 in human neutraphils (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
      Immunocytochemistry Analysis: A representative lot detected FPR1/2 in human neutraphils (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
      Immunoprecipitation Analysis: A representative lot immunoprecipitated FPR1/2 in neutraphils (Maaty, W.S., et al. (2013). JBC. 288(38):27042-27058).
      Western Blotting Analysis: A representative lot detected FPR1/2 in neutraphils (Maaty, W.S., et al. (2013). JBC. 288(38):27042-27058).
      Biological Information
      ImmunogenHis-tagged recombinant protein corresponding to the FPR1 (305-GQDFRERLI-313) and FPR2 (306- GQDFRERLI-314) of human FPR1/2.
      EpitopeFPR1 (305-GQDFRERLI-313) and FPR2 (306- GQDFRERLI-314)
      CloneNFPR1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityThis antibody is epitope mapped, recognizing cytoplasmic c-terminal tail residues of FPR1 (305-GQDFRERLI-313) and of FPR2 (306- GQDFRERLI-314) (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FPR1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~38 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in THP-1 cell lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected FPR1/2 in 10 µg of THP-1 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABF271 04055977159318

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies