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ABD101 Anti-ESRRB Antibody

This Anti-ESRRB Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of ESRRB.

Anti-ESRRB Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: ESRRB, ERRB2, ESRL2, NR3B2 UniProt Number: O95718
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ABD101
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABD101
      DescriptionAnti-ESRRB Antibody
      Alternate Names
      • Steroid hormone receptor ERR2
      • ERR beta-2
      • Estrogen receptor-like 2
      • Estrogen-related receptor beta
      • ERR-beta
      • Nuclear receptor subfamily 3 group B member 2
      Background InformationThe estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit Polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-ESRRB Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of ESRRB.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application Notes Immunocytochemical Analysis: 1:50 dilution of this antibody detected ESRRB in a mouse embryonic stem cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to Amino acids 376-388 of Human ESRRB protein.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Mouse
      Species Reactivity NoteMouse. Predicted to react with Human based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ESRRB
      • ERRB2
      • ESRL2
      • NR3B2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~56 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in a mouse brain E16 lysate. Western Blot Analysis: 1μg/ml of this antibody detected ESRRB in a mouse brain E16 lysate. Uncharacterized bands may be observed in some cell lysates with longer exposure times.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABD101 04053252986437

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies