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ABD77 Anti-Dax1 Antibody

This Dax1 antibody is validated for use in WB & IHC for the detection of the Dax1 protein.

Anti-Dax1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: NR0B1, DAX1, AHC UniProt Number: P51843
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ABD77
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABD77
      Replaces04-445
      DescriptionAnti-Dax1 Antibody
      Alternate Names
      • Nuclear receptor subfamily 0 group B member 1
      • DSS-AHC critical region on the X chromosome protein 1
      • Nuclear receptor DAX-1
      • AHC
      Background InformationDax-1 is an orphan nuclear receptor and is required for the normal development of the hypothalamic-pituitary-adrenal-gonadal axis formation. Defects in Dax-1 are the cause of X-linked adrenal hypoplasia congenital (XL-AHC); also known as X-linked Addison disease (AHX). Dax-1 also has a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency by acting as a negative regulator of Oct3/4 in ES cells.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Dax1 overexpressing HEK293 transfected cell line
      PresentationPurified rabbit polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Dax1 antibody is validated for use in WB & IHC for the detection of the Dax1 protein.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesEvaluated by Immunohistochemistry in Human and Rat adrenal gland tissue. Immunohistochemsitry Analysis: A 1:1000 dilution of this antibody detected Dax1 in Human and Rat glioblastoma adrenal gland tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the Region of Ligand binding of Human Dax1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      • Rat
      Species Reactivity NoteDemonstrated to react with Human and Rat Dax1. 75% Homologogous to Mouse Dax1
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NR0B1
      • DAX1
      • AHC
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~53 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in a Dax1 overexpressing HEK293 transfected cell line. Western Blot Analysis: A 1:2000 dilution of this antibody detected Dax1 in a Dax1 overexpressing HEK293 transfected cell line.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABD77 04053252847660

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies