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ABE1364 Anti-DMRT2 Antibody | ABE1364

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ABE1364
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE1364
      DescriptionAnti-DMRT2 Antibody | ABE1364
      Alternate Names
      • DSXL-2
      • Doublesex- and mab-3-related transcription factor 2
      • Doublesex-like 2 protein
      Background InformationDoublesex- and mab-3-related transcription factor 2 is encoded by the DMRT2 gene in human and directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to its early epaxial enhancer element. In addition, it is also involved in somite develoment during embryogenesis. The human protein shares a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 gene products involved in sex determination.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-DMRT2 Antibody is an antibody against DMRT2 for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected DMRT2 in human kidney and rat testis tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human DMRT2.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • DMRT2
      • DSXL2
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~70 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human kidney tissue lysate.

      Western Blotting Analysis: 0.25 µg/mL of this antibody detected DMRT2 in 10 µg of human kidney tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE1364 04055977137132