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ABT336 Anti-BCAR3 Antibody

Anti-BCAR3 Antibody is a highly specific rabbit polyclonal antibody, that targets Breast cancer Anti-estrogen resistance protein 3 & has been tested in western blotting.

Anti-BCAR3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Gene Symbol: BCAR3, NSP2, SH2D3B UniProt Number: O75815
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ABT336
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT336
      DescriptionAnti-BCAR3 Antibody
      Alternate Names
      • Breast cancer anti-estrogen resistance 3
      • NSP2
      • SH2D3B
      • Novel SH2-containing protein 2
      • SH2 domain-containing protein 3B
      • BCAR
      Background InformationBreast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Mouse kidney tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-BCAR3 Antibody is a highly specific rabbit polyclonal antibody, that targets Breast cancer Anti-estrogen resistance protein 3 & has been tested in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human BCAR3.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Mouse
      Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • BCAR3
      • NSP2
      • SH2D3B
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~104 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse kidney tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected BCAR3 in 15 µg of mouse kidney tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT336 04053252907043

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies