Millipore Sigma Vibrant Logo

MABN673 Anti-ARNTL Antibody, clone 1C5

Anti-ARNTL Antibody, clone 1C5 is a highly specific mouse monoclonal antibody, that targets ARNT-Like 1 & has been tested in western blotting & IHC.

Anti-ARNTL Antibody, clone 1C5 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: TIC, JAP3, MOP3, BMAL1, PASD3, BMAL1c, bHLHe5, MGC47515, ARNTL UniProt Number: O00327
View This Product on Sigma-Aldrich
MABN673
100 µL  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Replacement Information

      Special Offers

      100% Performance Guaranteed

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABN673
      DescriptionAnti-ARNTL Antibody, clone 1C5
      Alternate Names
      • Aryl hydrocarbon receptor nuclear translocator-like protein 1
      • Basic-helix-loop-helix-PAS protein MOP3
      • Brain and muscle ARNT-like 1
      • Class E basic helix-loop-helix protein 5
      • Short name=bHLHe5
      • Member of PAS protein 3
      • PAS domain-containing protein 3
      • bHLH-PAS protein JAP3
      Background InformationAryl hydrocarbon receptor nuclear translocator-like protein 1 or alternatively, Basic-helix-loop-helix PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5 (bHLHe5), Member of PAS protein 3, PAS domain-containing protein 3, bHLH-PAS protein JAP3, and encoded by the human gene ARNTL,BHLHE5, BMAL1, MOP3 or PASD3, is a protein belonging to the basic helix-loop-helix-PAS domain containing transcription factor family. ARNTL protein is important for the molecular mechanisms behind circadian rhythms as it interacts with a number of CLOCK (Circadian Locomotor Output Cycles Kaput) family members as well as CLOCK itself to promote transcription of a number of proteins of the circadian clock. ARNTL interacts with CRY and CRY2, PER, TIMELESS, and other clock related genes as well as non-CLOCK proteins such as HIF-1alpha (HIF1A) and SUMO3. ARNTL appears critical for proper function of rhythms, as only knockouts of ARNTL in mice generate mice that have upset biological clocks and a shorter lifespan. ARNTL is highly expressed in the adult brain as well as skeletal muscle and heart and ARNTL is a nuclear localized transcription activator. EMD-Millipore’s Anti-ARNTL mouse monoclonal antibody has been tested in western blot against recombinant transfected protein and in paraffin embedded immunohistochemistry on human spleen tissue sections.
      References
      Product Information
      FormatAscites
      Control
      • ARNTL-hIgGFc transfected HEK293 cell lysate
      PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-ARNTL Antibody, clone 1C5 is a highly specific mouse monoclonal antibody, that targets ARNT-Like 1 & has been tested in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected ARNTL in human spleen tissue.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenPurified recombinant fragment of human ARNTL expressed in E. Coli.
      Clone1C5
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • TIC
      • JAP3
      • MOP3
      • BMAL1
      • PASD3
      • BMAL1c
      • bHLHe5
      • MGC47515
      • ARNTL
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~100 kDa observed. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in ARNTL-hIgGFc transfected HEK293 cell lysate.

      Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected ARNTL-hIgGFc transfected HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN673 04053252917486

      Related Products & Applications

      Related Products

      Catalogue Number Description  
      AB2204 Anti-BMAL1 Antibody Show Pricing & Availability
      AB4140 Anti-MOP3 Antibody Show Pricing & Availability
      AB5436P Anti-Brain and Muscle ARNT-Like 1 Antibody Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies