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ABE607 Anti-APOBEC3G Antibody

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ABE607
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE607
      DescriptionAnti-APOBEC3G Antibody
      Alternate Names
      • DNA dC->dU-editing enzyme APOBEC-3G
      • APOBEC-related cytidine deaminase
      • APOBEC-related protein
      • ARCD
      • APOBEC-related protein 9
      • ARP-9
      • CEM-15
      • CEM15
      • Deoxycytidine deaminase
      Background InformationDNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G) is a member of the cytidine and deoxycytidylate deaminase family. APOBEC3G is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 alpha which targets incoming retroviral capsids, APOBEC3G plays an important role in cellular defense against retroviral infection. It is expressed in spleen, testes, ovary, peripheral blood leukocytes, and several tumor cell lines.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Caco-2 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect APOBEC-3G using this rabbit polyclonal antibody, Anti-APOBEC3G Antibody validated for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 1 µg/mL from a representative lot detected APOBEC3G in human spleen tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human APOBEC3G.
      EpitopeN-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the N-terminus of APOBEC3G.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • APOBEC3G
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~46 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting/Peptide Inhibition Assay Analysis in Caco-2 cell lysate.

      Western Blotting/Peptide Inhibition Assay Analysis: 5 µg/mL of this antibody detected APOBEC3G in 15 µg of Caco-2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE607 04053252878817