Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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100073
Sigma-Aldrich15-PGDH Inhibitor - CAS 1239610-60-6 - Calbiochem
The 15-PGDH Inhibitor controls the biological activity of 15-PGDH. This small molecule/inhibitor is primarily used for Membrane applications.
More>>The 15-PGDH Inhibitor controls the biological activity of 15-PGDH. This small molecule/inhibitor is primarily used for Membrane applications. Less<<
15-PGDH Inhibitor - CAS 1239610-60-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0–20 µM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively.
15-PGDH Inhibitor - CAS 1239610-60-6 - Calbiochem Certificates of Analysis
Title
Lot Number
100073
References
Reference overview
Wu, Y., et al. 2011. J. Med. Chem.54, 5260.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0–20 µM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively.
Form
Yellow solid
Intert gas (Yes/No)
Packaged under inert gas
CAS number
1239610-60-6
Chemical formula
C₁₉H₂₃NO₄S
Structure formula
Purity
≥99% by HPLC
Solubility
DMSO (100 mg/ml; clear, pale yellow solution)
Storage
Protect from light +2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
