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487910 (±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem

Nitric oxide donor that mimics the actions of nitric oxide, including relaxation of isolated bovine coronary artery rings (EC₅₀ = 130 nM).

(±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: SNAP

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487910
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Overview

Key Spec Table

CAS #Empirical Formula
79032-48-7C₇H₁₂N₂O₄S

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487910-1SETCN
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      487910-20MGCN
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          Description
          OverviewNitric oxide donor that mimics the actions of nitric oxide, including relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
          Catalogue Number487910
          Brand Family Calbiochem®
          SynonymsSNAP
          References
          ReferencesNishio, E., et al. 1996. Biochem. Biophys. Res. Commun. 221, 163.
          Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
          Fehsel, K., et al. 1995. J. Immunol. 155, 2858.
          Gopalkrishna, R., et al. 1993. J. Biol. Chem. 268, 27180.
          Southan, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107.
          Henry, P.J., et al. 1989. J. Pharmacol. Exp. Ther. 248, 762.
          Product Information
          CAS number79032-48-7
          ATP CompetitiveN
          FormPale green solid
          Hill FormulaC₇H₁₂N₂O₄S
          Chemical formulaC₇H₁₂N₂O₄S
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Biological Information
          Primary TargetNitric oxide donor
          Primary Target IC<sub>50</sub>EC50 = 130 nM in relaxation of isolated bovine coronary artery rings
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsSNAP evolves NO immediately upon solubilization; reconstitute just prior to use.
          Global Trade Item Number
          Catalogue Number GTIN
          487910-1SETCN 04055977200324
          487910-20MGCN 04055977200331