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569406 Stearoyl-CoA Desaturase 1 Inhibitor, MF-438 - Calbiochem

Stearoyl-CoA Desaturase 1 Inhibitor, MF-438, CAS 921605-87-0, is a cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1; IC50 of 2.3 nM).

Stearoyl-CoA Desaturase 1 Inhibitor, MF-438 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole

569406
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Panoramica

Replacement Information

Products

Numero di catalogoConfezionamento Qtà/conf
569406-10MG Bottiglia di vetro 10 mg
Description
OverviewA cell-permeable, thiadiazole-pyridazine compound that acts as an inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC50 of 2.3 nM. In vivo, it exhibits an ED50 of 1-3 mg/kg, p.o., in mouse liver PD assays.
Catalogue Number569406
Brand Family Calbiochem®
Synonyms2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole
References
ReferencesLeger, S., et al. 2010. Bioorg Med Chem Lett. 2, 499.
Product Information
FormOff-white powder
Hill FormulaC₁₉H₁₈F₃N₅OS
Chemical formulaC₁₉H₁₈F₃N₅OS
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationStearoyl-CoA Desaturase 1 Inhibitor, MF-438, CAS 921605-87-0, is a cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1; IC50 of 2.3 nM).
Biological Information
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
569406-10MG 04055977190557

Documentation

Stearoyl-CoA Desaturase 1 Inhibitor, MF-438 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Stearoyl-CoA Desaturase 1 Inhibitor, MF-438 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
569406

Riferimenti bibliografici

Panoramica delle referenze
Leger, S., et al. 2010. Bioorg Med Chem Lett. 2, 499.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-May-2013 JSW
Synonyms2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole
DescriptionA cell-permeable, thiadiazole-pyridazine compound that acts as an inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC50 of 2.3 nM. In vivo, it exhibits an ED50 of 1-3 mg/kg, p.o., in mouse liver PD assays.
FormOff-white powder
Chemical formulaC₁₉H₁₈F₃N₅OS
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (10 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesLeger, S., et al. 2010. Bioorg Med Chem Lett. 2, 499.