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03-209 SET7/9 human recombinant - Methyltransferase enzyme

Human recombinant SET7/9 expressed in E. Coli.

SET7/9 human recombinant - Methyltransferase enzyme: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Key Applications: Enzyme Assays UniProt Number: Q8WTS6
03-209
100 µg  
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Replacement Information

Tabella delle specifiche principali

Key ApplicationsSpeciesUni Prot Number
Enzyme AssaysHuman Q8WTS6
Description
Catalogue Number03-209
Brand Family Upstate
Trade Name
  • Upstate
DescriptionSET7/9 human recombinant - Methyltransferase enzyme
OverviewHuman recombinant SET7/9 expressed in E. Coli
Background InformationThe methylation of histones plays a pivotal role in the regulation of chromatin structure and gene expression. Histone methylation can occur on Arg or Lys residues, with an exquisite site selectivity for Lys methylation at specific positions in the N-termini of histones H3 and H4. SET7/9, a histone methyltransferase (HMTase), which transfers methyl groups to Lys4 of Histone H3, forms a complex with S-adenosyl-L-methionine. This complex contains an active site consisting of a binding pocket where an AdoMet molecule, in an unusual conformation, binds a narrow substrate-specific channel that only unmethylated lysine residues can access, and a catalytic tyrosine residue.
References
Product Information
FormatPurified
PresentationIn liquid containing 50 mM Tris-HCl, pH 7.5, containing 0.2 M sodium chloride, 5 mM DTT and 20% glycerol. Frozen solution.
Quality LevelMQ100
Applications
ApplicationHuman recombinant SET7/9 expressed in E. Coli.
Key Applications
  • Enzyme Assays
Application NotesMethyltransferase assays
Biological Information
Concentration1 mg/mL
PurityPurity >95% by SDS-PAGE
Specific Activity<1.0EU/µg protein (LAL test)
UniProt Number
Molecular Weight~41 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 12 months at -20°C from date of receipt. Avoid multiple freeze/thaw cycles.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
03-209 04053252550867