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539165 Proteasome Inhibitor Set II - Calbiochem

539165
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Products

Numero di catalogoConfezionamento Qtà/conf
539165-1SET Bottiglia di vetro 1 set
Description
OverviewContains 5 mg of ALLN (Cat. No. 208719), 100 μg each of Epoxomicin (Cat. No. 324800), and clasto-Lactacystin β-Lactone (Cat. No. 426102). Supplied with a data sheet.
Catalogue Number539165
Brand Family Calbiochem®
References
Product Information
FormSolid
Quality LevelMQ100
Applications
Biological Information
Primary Targetcalpain 1, calpain 2
Secondary targetcathepsin B, cathepsin L
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
539165-1SET 07790788051303

Documentation

Proteasome Inhibitor Set II - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Proteasome Inhibitor Set II - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
539165

Brochure

Titolo
Caspases and other Apoptosis Related Tools Brochure
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-September-2008 RFH
DescriptionProteasomes are large multi-subunit protease complexes, which selectively degrade intracellular proteins. A protein marked for degradation is attached to multiple molecules of ubiquitin, a 76-amino acid protein, which escorts it for rapid hydrolysis, by the 26S proteasome. The proteolytic core of this complex consists of the 20S proteasome, which contains multiple peptidase activities and has a molecular mass of ~700 kDa. Recently several potent, cell-permeable proteasome inhibitors have been developed.

The Calbiochem® brand offers a set that includes 3 proteasome inhibitors with varying inhibtory effects.

The table below outlines some of the physical and biological properties of these compounds.
FormSolid
Intert gas (Yes/No) Packaged under inert gas
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Toxicity Standard Handling