52332 Sigma-AldrichPhenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem
Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues.
More>> Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues. Less<<Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Sinonimi: Benzylsulfonyl Fluoride, PMSF
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Panoramica
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Tabella delle specifiche principali
| CAS # | Empirical Formula |
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| 329-98-6 | C₇H₇FO₂S |
Products
| Numero di catalogo | Confezionamento | Qtà/conf | |
|---|---|---|---|
| 52332-1GM | Fusto in alluminio | 1 gm | |
| 52332-25GM | Scatola di cartone | 25 gm | |
| 52332-5GM | Bottiglia di vetro | 5 gm |
| Description | |
|---|---|
| Overview | Irreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor, see AEBSF (Cat. No. 101500). |
| Catalogue Number | 52332 |
| Brand Family | Calbiochem® |
| Synonyms | Benzylsulfonyl Fluoride, PMSF |
| Product Information | |
|---|---|
| CAS number | 329-98-6 |
| ATP Competitive | N |
| Form | White to off-white crystalline solid |
| Hill Formula | C₇H₇FO₂S |
| Chemical formula | C₇H₇FO₂S |
| Reconstitution | t½ = 1 hour at pH 7.5. Effective concentration: 50 μM. |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ200 |
| Applications |
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| Biological Information | |
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| Primary Target | serine proteases |
| Purity | ≥99% by GC |
| Physicochemical Information | |
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| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS | |
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| RTECS | XT8040000 |
| Product Usage Statements |
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| Packaging Information |
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| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Numero di catalogo | GTIN |
| 52332-1GM | 07790788051044 |
| 52332-25GM | 04055977271508 |
| 52332-5GM | 04055977271515 |
Documentation
Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem MSDS
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Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem Certificati d'Analisi
| Titolo | Numero di lotto |
|---|---|
| 52332 |
Riferimenti bibliografici
| Panoramica delle referenze |
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| Seitz, R., et al. 1993. Int. J. Cancer 53, 514. Weaver, V.M., et al. 1993. Biochem. Cell. Biol. 71, 488. Bourgain, R.H., et al. 1992. Adv. Exp. Med. Biol. 316, 427. Chang, C.T., et al. 1992. Biochem. Int. 28, 707. |
Brochure
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| Caspases and other Apoptosis Related Tools Brochure |
Citazioni
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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