Pellicon® XL 50 Ultrafiltration Cassettes - Ultrafiltration
True Linear scalability with UF membranes with the same flow path and channel height as larger Pellicon® 2 cassettes. The Pellicon® XL 50 allows process development and scaling studies.
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True Linear scalability with UF membranes with the same flow path and channel height as larger Pellicon® 2 cassettes. The Pellicon® XL 50 allows process development and scaling studies. Meno
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Prodotti consigliati
Panoramica
Specifiche tecniche
Informazioni per l’ordine
Documentation
Riferimenti bibliografici
| Panoramica dei riferimenti bibliografici |
|---|
| Scaling Up with Tangenital Flow Filtration Campbell, Melissa; Coons, Elizabeth GEN; v. 21, no. 16; Sept. 15, 2001, p. 60 2001 |
| Validation of Tangential Flow Filtration (TFF) Systems Michaels, Stephen L. Journal of Parenteral Science and Technology (Sept/Oct 1991). 1991 |
FAQ
| Domanda | Risposta |
|---|---|
| What is the sample volume range for the Pellicon II Mini system? | The Pellicon II Mini system is capable of volumes in the approximate range of 1- 50 L concentrating down to 100 mL. More or less volume can be processed depending on the individual needs of the operation, ie. process time, sensitivity of product, etc. |
| What is the part number for the Gauge Kit that is used with the Pellicon XL? | Gauge Kit for Pellicon XL Device (0-60 psi): Part number XXPXLGAGE, 1 per kit. Includes an inlet pressure gauge and t-fitting. This gauge is recommended when the Pellicon is used in the absence of a Labscale TFF system in order to ensure that the pressure on the tubing is known and not allowed to exceed it's recommended maximum. |
Prodotti e applicazioni correlate
Linee di prodotti
Pellicon® 2 Microfiltration CassettesA new standard in cassette style tangential flow filtration devices.Per saperne di più >> |
Prodotti correlati per: Application Facete
| Antibody Purification |
| Dialysis and Filtration |
Prodotti correlati per: Brand Facete
| Pellicon® |
Categorie
| Biopharmaceutical Manufacturing > Downstream Processing > Ultrafiltration |
Small volume convenience yields high-end results with Millipore’s Pellicon® XL 50 Microfiltration Cassette. This high-performance tangential flow filter is the ideal choice for anyone contending with:
- Process Development Work (50 to 1000 mL range)
- Small Volume Processing
- Membrane Research
Durapore® Membranes
The long established Durapore® hydrophilic PVDF microfiltration membrane is well known for its exceptional combination of high flux, low protein binding, and high product recoveries.
Pellicon® XL 50 cassettes are 100% integrity tested in manufacturing to ensure consistent and reliable performance.
Benefits
- Superior performance – its controlled channel height capability yields consistent, reliable and predictable results.
- Hyper Hydrophilic – Durapore’s superior hydrophilic membranes provide the lowest binding of proteins and other biologicals among all commercially available microporous membranes.
- Void-free Technology – guards against solute leakage.
- Self Contained – no holder required.
Applications
- Harvest, washing and clarification – of cell cultures, lysates and fermentation broths.
- Clinical trial support – quick preparation of materials
- Membrane selection – to study membrane efficacy
- Sample preparation – leaving larger equipment available
- Small volume manufacturing – same quality on a smaller scale
| Specifications | |
| Materials of Construction | |
| Membranes: | Hydrophilic polyvinylidene fluoride (Durapore® membrane) |
| Screens, Exterior housing, Fittings/connectors and Luer Caps: | Polypropylene |
| Fittings | Female Luer |
| Filtration Area | 50 cm² (0.05 ft² ) |
| Device Width | 3.0 cm (1.2 in.) |
| Device Length | 18.8 cm (7.4 in.) |
| Hold-up Volume (typical) | 3.2 mL |
| Maximum Operating Pressure | 5.6 bar (80 psig) |
| Optimum Tangential Flow Rate for Polarized Solutions | 30 – 50 mL/min |
| Membrane pH Compatibility | 1.5 – 9 (continuous) 1 – 11 (cleaning) |
| Biocompatibility/Toxicity | All wetted parts have been tested and meet the requirements of the USP Class VI Biological Test for Plastics. |
| Extractables | Gravimetric extractables level < 7.5 mg/ device after RO water flush. USP oxidizables test negative after RO water flush. |
| Prefiltration Requirements | Prefiltration of sample using 100 μm nominal pore size filter is recommended. |