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475984 MyoVin-1 - CAS 1259177-59-7 - Calbiochem

A pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V.

MyoVin-1 - CAS 1259177-59-7 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Myosin V Inhibitor 1

475984
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Products

Numero di catalogoConfezionamento Qtà/conf
475984-5MG Bottiglia di vetro 5 mg
Description
OverviewA pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V (Ki = 6.3 and 5.5 µM by single- and double-headed myosin V). Displays excellent selectivity over myosin II and myosin IV (< 10 % inhibition at 50 µM) and only minimally inhibits the kinase activity of Cdk1/B, CHK1, Plk1, Abl, ERK2, CKII and Aurora-B (< 10 % inhibition at 100 µM).
Catalogue Number475984
Brand Family Calbiochem®
SynonymsMyosin V Inhibitor 1
References
ReferencesIslam, K., et al. 2010. Angew. Chem. Int. Ed. 49, 8484.
Product Information
CAS number1259177-59-7
FormPale yellow powder
Hill FormulaC₂₉H₂₆N₆O₃S
Chemical formulaC₂₉H₂₆N₆O₃S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
475984-5MG 04055977184372

Documentation

MyoVin-1 - CAS 1259177-59-7 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

MyoVin-1 - CAS 1259177-59-7 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
475984

Riferimenti bibliografici

Panoramica delle referenze
Islam, K., et al. 2010. Angew. Chem. Int. Ed. 49, 8484.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-November-2012 JSW
SynonymsMyosin V Inhibitor 1
DescriptionA pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V (Ki = 6.3 and 5.5 µM by single- and double-headed myosin V). Displays excellent selectivity over myosin II and myosin IV (< 10 % inhibition at 50 µM) and only minimally inhibits the kinase activity of Cdk1/B, CHK1, Plk1, Abl, ERK2, CKII and Aurora-B (< 10 % inhibition at 100 µM).
FormPale yellow powder
Intert gas (Yes/No) Packaged under inert gas
CAS number1259177-59-7
Chemical formulaC₂₉H₂₆N₆O₃S
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (50 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesIslam, K., et al. 2010. Angew. Chem. Int. Ed. 49, 8484.