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444218 MMP-3 Inhibitor I - Calbiochem

The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MMP-3 Inhibitor I - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor

Primary Target: MMP-3
444218
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical Formula
C₂₇H₄₆N₁₀O₉S

Products

Numero di catalogoConfezionamento Qtà/conf
444218-5MG Fiala di plastica 5 mg
Description
OverviewInhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
Catalogue Number444218
Brand Family Calbiochem®
SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
References
ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Product Information
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a trifluroacetate salt.
Hill FormulaC₂₇H₄₆N₁₀O₉S
Chemical formulaC₂₇H₄₆N₁₀O₉S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-3
Primary Target IC<sub>50</sub>5 µM against MMP-3
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
444218-5MG 04055977205220

Documentation

MMP-3 Inhibitor I - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

MMP-3 Inhibitor I - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
444218

Riferimenti bibliografici

Panoramica delle referenze
Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

Citazioni

Titolo
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•
    Scheda tecnica

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision31-January-2008 JSW
    SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
    DescriptionInhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
    FormWhite solid
    FormulationSupplied as a trifluroacetate salt.
    Chemical formulaC₂₇H₄₆N₁₀O₉S
    Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
    Purity≥90% by HPLC
    SolubilityH₂O (1 mg/ml)
    Storage -20°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
    Toxicity Standard Handling
    ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
    Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
    Citation
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•