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475882 ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem

A cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM).

ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl

Primary Target: Mlck
475882
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Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
105637-50-1C₁₅H₁₇ClN₂O₂S · HCl

Products

Numero di catalogoConfezionamento Qtà/conf
475882-1MG Fiala di plastica 1 mg
Description
OverviewA cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM). Also inhibits catecholamine secretion in intact and permeabilized chromaffin cells.
Catalogue Number475882
Brand Family Calbiochem®
Synonyms1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl
References
ReferencesReig, J.A., et al. 1993. Neurochem. Res. 18, 317.
Nagatsu, T., et al. 1987. Biochem. Biophys. Res. Commun. 143, 1045.
Saitoh, M., et al. 1987. J. Biol. Chem. 262, 7796.
Saitoh, M., et al. 1986. Biochem. Biophys. Res. Commun. 140, 280.
Product Information
CAS number105637-50-1
ATP CompetitiveY
FormWhite solid
Hill FormulaC₁₅H₁₇ClN₂O₂S · HCl
Chemical formulaC₁₅H₁₇ClN₂O₂S · HCl
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMlck
Primary Target K<sub>i</sub>3.8 µM, 32 µM, 54 µM against myosin light chain kinase, protein kinase A, and protein kinase C, respectively
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
475882-1MG 04055977203509

Documentation

ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
475882

Riferimenti bibliografici

Panoramica delle referenze
Reig, J.A., et al. 1993. Neurochem. Res. 18, 317.
Nagatsu, T., et al. 1987. Biochem. Biophys. Res. Commun. 143, 1045.
Saitoh, M., et al. 1987. J. Biol. Chem. 262, 7796.
Saitoh, M., et al. 1986. Biochem. Biophys. Res. Commun. 140, 280.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2018 JSW
Synonyms1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl
DescriptionA cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM). Also inhibits catecholamine secretion in intact and permeabilized chromaffin cells.
FormWhite solid
CAS number105637-50-1
Chemical formulaC₁₅H₁₇ClN₂O₂S · HCl
Structure formulaStructure formula
Purity≥98% by TLC
Solubility50% Ethanol (10 mg/ml). Further dilute with aqueous buffer just prior to use.
Storage Protect from light
+2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Toxicity Standard Handling
ReferencesReig, J.A., et al. 1993. Neurochem. Res. 18, 317.
Nagatsu, T., et al. 1987. Biochem. Biophys. Res. Commun. 143, 1045.
Saitoh, M., et al. 1987. J. Biol. Chem. 262, 7796.
Saitoh, M., et al. 1986. Biochem. Biophys. Res. Commun. 140, 280.