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HRNKLMAG-51K-01 MILLIPLEX MAP Human RANKL Magnetic Bead- Single Plex - Metabolism Assay

HRNKLMAG-51K-01
96-well plate  
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
RANKL HMplexLuminex xMAP
Description
Catalogue NumberHRNKLMAG-51K-01
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Human RANKL Magnetic Bead- Single Plex - Metabolism Assay
Background InformationBone metabolism is the dynamic process of ongoing bone deposition and re-absorption, controlled by osteoblasts, osteocytes, and osteoclasts. While osteoblasts and osteocytes (osteoblasts surrounded by matrix) are responsible for bone deposition, osteoclasts are responsible for bone resorption. Both are required to maintain bone structure, as well as an adequate supply of calcium. To maintain this metabolic balance these cells rely on complex signaling pathways involving hormones and cytokines to achieve the appropriate rates of growth and differentiation.

One of these proteins, Receptor Activator for Nuclear Factor B Ligand (RANKL) activates osteoclasts and has been implicated in degenerative bone diseases such as rheumatoid arthritis and osteomyelitis.
References
Product Information
Detection methodLuminex xMAP
ConfigurationSingle Plex
Precision, %
  • Inter-assay: <15
  • Intra-assay: <10
Panel TypeMAGNETIC Bone
Quality LevelMQ200
Applications
ApplicationThis MILLIPLEX MAP Human RANKL Magnetic Bead- Single Plex, HRNKLMAG-51K-01 is a Metabolism single plex assay. The analyte available for this kit is RANKL.
Key Applications
  • Multiplexing
Application Notes• Same day or overnight incubation (recommended)
• Samples can be run neat or diluted 1:2 (recommended) for human serum, plasma and tissue culture supernatants (25uL/well)
Biological Information
Species Reactivity
  • Human
Analytes Available
  • RANKL
Assay PanelEverything you need in a single kit.
UniProt Number
Accuracy
  • 92%
Physicochemical Information
Sensitivity
  • 5.0 pg/mL
Linearity of DilutionContact technical support for information.
Standard Curve Range
  • 4.88-20,000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
HRNKLMAG-51K-01 04055977289060