573129 Sigma-AldrichInSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem
The InSolution™ STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The InSolution™ STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
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Panoramica
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Tabella delle specifiche principali
| Empirical Formula |
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| C₁₇H₁₄BrN₃O |
Products
| Numero di catalogo | Confezionamento | Qtà/conf | |
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| 573129-5MG | Bottiglia di vetro | 5 mg |
| Description | |
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| Overview | A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC50 = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo. Shown to cross blood-brain barrier in mice in vivo. |
| Catalogue Number | 573129 |
| Brand Family | Calbiochem® |
| References | |
|---|---|
| References | Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
| Product Information | |
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| Form | Liquid |
| Formulation | A 50 mM (5 mg/281 µl) solution of STAT3 Inhibitor III, WP1066 (Cat. No. 573097) in DMSO. |
| Hill Formula | C₁₇H₁₄BrN₃O |
| Chemical formula | C₁₇H₁₄BrN₃O |
| Hygroscopic | Hygroscopic |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥97% by HPLC |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information | |
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| R Phrase | R: 36/38 Irritating to eyes and skin. |
| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Numero di catalogo | GTIN |
| 573129-5MG | 04055977190199 |
Documentation
InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem MSDS
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InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem Certificati d'Analisi
| Titolo | Numero di lotto |
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| 573129 |
Riferimenti bibliografici
| Panoramica delle referenze |
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| Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
Informazioni tecniche
| Titolo |
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| JAK/STAT Signaling Research Focus |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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