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513001 InSolution™ PD 98059 - CAS 167869-21-8 - Calbiochem

513001
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Tabella delle specifiche principali

CAS #Empirical Formula
167869-21-8C₁₆H₁₃NO₃

Products

Numero di catalogoConfezionamento Qtà/conf
513001-1ML Bottiglia di vetro 1 ml
Description
Catalogue Number513001
Brand Family Calbiochem®
SynonymsMEK Inhibitor V
References
ReferencesKültz, D., et al. 1998. J. Biol. Chem. 273, 13645.
Dudley, D.T., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 7686.
Langlois, W.J., et al. 1995. J. Biol. Chem. 270, 25320.
Pang, L., et al. 1995. J. Biol. Chem. 270, 13585.
Waters, S.B., et al. 1995. J. Biol. Chem. 270, 20883.



Selected Citations
Lee, J., et al. 2009. Cell Stem Cell 5, 76.


Product Information
CAS number167869-21-8
ATP CompetitiveN
FormLiquid
FormulationA 5 mg/ml solution of PD 98059 (Cat. No. 513000) in anhydrous DMSO.
Hill FormulaC₁₆H₁₃NO₃
Chemical formulaC₁₆H₁₃NO₃
ReversibleY
Quality LevelMQ100
Applications
ApplicationInSolution™ PD 98059, CAS 167869-21-8, is a 5 mg/ml solution in DMSO. A a cell-permeable, selective & reversible inhibitor of MAP Kinase Kinase (MEK).
Biological Information
Primary TargetMAP kinase kinase (MEK)
Primary Target IC<sub>50</sub>2 µM in completely blocking the 4-fold increase in MAP kinase activity produced by nerve growth factor in PC12 cells
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Numero di catalogo GTIN
513001-1ML 07790788050924