440204 Sigma-AldrichInSolution™ LY 294002 - CAS 154447-36-6 - Calbiochem
InSolution™ LY 294002, CAS 154447-36-6, is a 10 mM solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4 µM).
More>> InSolution™ LY 294002, CAS 154447-36-6, is a 10 mM solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4 µM). Less<<Sinonimi: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, BRD2 Inhibitor IV, BRD3 Inhibitor III, BRD4 Inhibitor IV
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Replacement Information |
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Tabella delle specifiche principali
CAS # | Empirical Formula |
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154447-36-6 | C₁₉H₁₇NO₃ |
Products
Numero di catalogo | Confezionamento | Qtà/conf | |
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440204-1MG | Fiala di plastica | 1 mg |
Description | |
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Catalogue Number | 440204 |
Brand Family | Calbiochem® |
Synonyms | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, BRD2 Inhibitor IV, BRD3 Inhibitor III, BRD4 Inhibitor IV |
References | |
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References | Dittman, A., et al. 2013. ACS Chem. Biol. 9, 495. Baumann, P., and West, S.C. 1998. Proc. Natl. Acad. Sci. USA 95, 14066. Cardone, M.H., et al. 1998. Science 282, 1318. Vlahos, C.J., et al. 1995. J. Immunol. 154, 2413. Yano, H., et al. 1995. Biochem. J. 312, 145. Vlahos, C.J., et al. 1994. J. Biol. Chem. 269, 5241. Selected Citations Lee, J., et al. 2009. Cell Stem Cell 5, 76. |
Product Information | |
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CAS number | 154447-36-6 |
ATP Competitive | Y |
Form | Liquid |
Formulation | A 10 mM (1 mg/325 µl) solution of LY 294002 (Cat. No. 440202) in DMSO. |
Hill Formula | C₁₉H₁₇NO₃ |
Chemical formula | C₁₉H₁₇NO₃ |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | phosphatidylinositol 3-kinase |
Primary Target IC<sub>50</sub> | 1.4 µM against phosphatidylinositol 3-kinase |
Purity | ≥98% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Numero di catalogo | GTIN |
440204-1MG | 04055977186710 |
Documentation
InSolution™ LY 294002 - CAS 154447-36-6 - Calbiochem MSDS
Titolo |
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InSolution™ LY 294002 - CAS 154447-36-6 - Calbiochem Certificati d'Analisi
Titolo | Numero di lotto |
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440204 |
Riferimenti bibliografici
Panoramica delle referenze |
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Dittman, A., et al. 2013. ACS Chem. Biol. 9, 495. Baumann, P., and West, S.C. 1998. Proc. Natl. Acad. Sci. USA 95, 14066. Cardone, M.H., et al. 1998. Science 282, 1318. Vlahos, C.J., et al. 1995. J. Immunol. 154, 2413. Yano, H., et al. 1995. Biochem. J. 312, 145. Vlahos, C.J., et al. 1994. J. Biol. Chem. 269, 5241. Selected Citations Lee, J., et al. 2009. Cell Stem Cell 5, 76. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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