218861 Sigma-AldrichInSolution™ Casein Kinase II Inhibitor III, TBCA - CAS 934358-00-6 - Calbiochem
The InSolution™ Casein Kinase II Inhibitor III, TBCA, also referenced under CAS 934358-00-6, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The InSolution™ Casein Kinase II Inhibitor III, TBCA, also referenced under CAS 934358-00-6, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<InSolution™ Casein Kinase II Inhibitor III, TBCA - CAS 934358-00-6 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Sinonimi: (E)-3-(2,3,4,5-Tetrabromophenyl)acrylic acid
Prodotti consigliati
Panoramica
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Tabella delle specifiche principali
| CAS # | Empirical Formula |
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| 934358-00-6 | C₉H₄Br₄O₂ |
Products
| Numero di catalogo | Confezionamento | Qtà/conf | |
|---|---|---|---|
| 218861-5MG | Bottiglia di vetro | 5 mg |
| Description | |
|---|---|
| Overview | A cell-permeable tetrabrominated cinnamic acid compound that acts as a potent and ATP-competitive inhibitor of Casein Kinase II (IC50 = 110 nM, Ki = 77 nM) with greater selectivity than TBB (Cat. No. 218697 and Cat. No. 218708) and DMAT (Cat. No. 218699 and Cat. No. 218706) against a panel of 28 commonly studied kinases. Shown to efficiently induce apoptosis in Jurkat cells (DC50 = 7.7 µM). The solid form of this compound (Cat. No. 218710) is also available. |
| Catalogue Number | 218861 |
| Brand Family | Calbiochem® |
| Synonyms | (E)-3-(2,3,4,5-Tetrabromophenyl)acrylic acid |
| References | |
|---|---|
| References | Pagano, M.A., et al. 2006. Chembiochem,/i> 8, 129. |
| Product Information | |
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| CAS number | 934358-00-6 |
| Form | Liquid |
| Formulation | A 25 mM (5 mg/431 µL) solution of Casein Kinase II Inhibitor III, TBCA (Cat. No. 218710) in DMSO. |
| Hill Formula | C₉H₄Br₄O₂ |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | CKII |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Numero di catalogo | GTIN |
| 218861-5MG | 04055977201970 |
Documentation
InSolution™ Casein Kinase II Inhibitor III, TBCA - CAS 934358-00-6 - Calbiochem MSDS
| Titolo |
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InSolution™ Casein Kinase II Inhibitor III, TBCA - CAS 934358-00-6 - Calbiochem Certificati d'Analisi
| Titolo | Numero di lotto |
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| 218861 |
Riferimenti bibliografici
| Panoramica delle referenze |
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| Pagano, M.A., et al. 2006. Chembiochem,/i> 8, 129. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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