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345731 GDF-5, Mouse, Recombinant

GDF-5, Mouse, Recombinant, consists of amino acids 376-495 and is expressed in E. coli with and without an N-terminal methionine. Involved in myogenesis, bone morphogenesis & neuron differentiation.

GDF-5, Mouse, Recombinant: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Cartilage-derived morphogenetic protein 1 (CDMP-1)

345731
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Purity
≥95% by SDS-PAGE

Products

Numero di catalogoConfezionamento Qtà/conf
345731-50UG Bottiglia di vetro 50 μg
Description
OverviewRecombinant, mouse growth differentiation factor 5 (GDF-5) consisting of amino acids 376-495, expressed in E. coli with and without an N-terminal methionine. GDF-5, a member of the bone morphogenetic protein family, is involved in regulation of myogenesis, bone morphogenesis, neuron differentiation and survival, and chondrogenesis regulation.
Catalogue Number345731
Brand Family Calbiochem®
SynonymsCartilage-derived morphogenetic protein 1 (CDMP-1)
References
ReferencesSettle, S.H., Jr., et al. 2003. Dev. Biol. 254, 116.
Massague, J., et al. 2000. Genes and Dev. 14, 627.
FrancisWest, P.H., et al. 1999.
Development 126, 1035. Inada, M., et al. 1996. BBRC 222, 317.
Nishitoh, H., et al. 1996. J. Biol. Chem. 271, 21345.
Storm, E.E., et al. 1994. Nature 368, 639.
Product Information
FormSolid
FormulationLyophilized from 0.2 µm filter-sterilized Acetonitrile, TFA, BSA.
Quality LevelMQ100
Applications
ApplicationGDF-5, Mouse, Recombinant, consists of amino acids 376-495 and is expressed in E. coli with and without an N-terminal methionine. Involved in myogenesis, bone morphogenesis & neuron differentiation.
Biological Information
Biological activityED₅₀ = 1-4 µg/ml as measured by induction of alkaline phosphatase production by ATDC5 mouse chondrogenic cells. (Nakamura, K. et al. 1999. Exp. Cell Res. 250, 351.)
Purity≥95% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <1.0 EU/µg protein
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
345731-50UG 04055977193817

Documentation

GDF-5, Mouse, Recombinant MSDS

Titolo

Scheda di sicurezza (MSDS) 

GDF-5, Mouse, Recombinant Certificati d'Analisi

TitoloNumero di lotto
345731

Riferimenti bibliografici

Panoramica delle referenze
Settle, S.H., Jr., et al. 2003. Dev. Biol. 254, 116.
Massague, J., et al. 2000. Genes and Dev. 14, 627.
FrancisWest, P.H., et al. 1999.
Development 126, 1035. Inada, M., et al. 1996. BBRC 222, 317.
Nishitoh, H., et al. 1996. J. Biol. Chem. 271, 21345.
Storm, E.E., et al. 1994. Nature 368, 639.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-September-2011 RFH
SynonymsCartilage-derived morphogenetic protein 1 (CDMP-1)
DescriptionRecombinant, mouse growth differentiation factor 5 (GDF-5) consisting of amino acids 376-495, expressed in E. coli with and without an N-terminal methionine. GDF-5, a member of the bone morphogenetic protein family, is involved in regulation of myogenesis, bone morphogenesis, neuron differentiation and survival, and chondrogenesis regulation.
FormSolid
FormulationLyophilized from 0.2 µm filter-sterilized Acetonitrile, TFA, BSA.
Purity≥95% by SDS-PAGE
ContaminantsEndotoxin: <1.0 EU/µg protein
Biological activityED₅₀ = 1-4 µg/ml as measured by induction of alkaline phosphatase production by ATDC5 mouse chondrogenic cells. (Nakamura, K. et al. 1999. Exp. Cell Res. 250, 351.)
SolubilityReconstitute to 150 µg/ml in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSettle, S.H., Jr., et al. 2003. Dev. Biol. 254, 116.
Massague, J., et al. 2000. Genes and Dev. 14, 627.
FrancisWest, P.H., et al. 1999.
Development 126, 1035. Inada, M., et al. 1996. BBRC 222, 317.
Nishitoh, H., et al. 1996. J. Biol. Chem. 271, 21345.
Storm, E.E., et al. 1994. Nature 368, 639.