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298711 Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem

Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles.

Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Diethyl Oxydiformate, DEPC

Primary Target: Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle
298711
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Tabella delle specifiche principali

CAS #Empirical Formula
1609-47-8C₆H₁₀O₅

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298711-100GM Bottiglia di vetro 100 gm
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298711-25GM Fiala di plastica 25 gm
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Description
OverviewInhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. Useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Also inhibits platelet-activating factor acetyl hydrolase. Has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.
Catalogue Number298711
Brand Family Calbiochem®
SynonymsDiethyl Oxydiformate, DEPC
References
ReferencesShoshan-Barmatz, V., and Weil, S. 1994. Biochem. J. 299, 177.
Blumbers, D.O. 1987. Methods Enzymol. 152, 20.
Product Information
CAS number1609-47-8
ATP CompetitiveN
FormClear colorless liquid
Hill FormulaC₆H₁₀O₅
Chemical formulaC₆H₁₀O₅
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetInhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle
Purity≥96% by titration
Physicochemical Information
Cell permeableN
Safety Information according to GHS
RTECSLQ9350000
Safety Information
R PhraseR: 22-36/37/38

Harmful if swallowed.
Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Global Trade Item Number
Numero di catalogo GTIN
298711-100GM 04055977197952
298711-25GM 07790788049041