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DPP4 DPP IV Inhibitor

DPP4
1 mL  
Purchase on Sigma-Aldrich

Panoramica

Replacement Information
Description
Catalogue NumberDPP4
DescriptionDPP IV Inhibitor
References
Product Information
HS Code3822 19 90
Quality LevelMQ100
Applications
Biological Information
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.
Gene Symbol
  • DPP4
  • CD26
  • ADCP2
  • DPPIV
  • ADABP
  • TP103
  • EC 3.4.14.5 [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form)
  • Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P27487 # Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. Plays a role in T-cell activation.
SIZE: 766 amino acids; 88279 Da
SUBUNIT: Homodimer or heterodimer with Seprase (FAP).
SUBCELLULAR LOCATION: Dipeptidyl peptidase 4 soluble form: Secreted. & Cell membrane; Single-pass type II membrane protein.
TISSUE SPECIFICITY: Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.
PTM: The soluble form (SDPP) derives from the membrane form (MDPP) by proteolytic processing.
SIMILARITY: SwissProt: P27487 ## Belongs to the peptidase S9B family. DPPIV subfamily.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Storage ConditionsUpon arrival, store at 4°C. For long-term of more than 2 weeks, store at –20°C.
Packaging Information
Material Size1 mL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
DPP4 04053252362330