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204902 Complement C5a des-Arg, Human

Complement C5a des-Arg, Human, is a native, single chain glycopeptide (73 aa). Once produced, C5a is converted to C5a des-Arg upon removal of the C-terminal arginine by serum carboxypeptidase N.

Complement C5a des-Arg, Human: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
204902
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Numero di catalogoConfezionamento Qtà/conf
204902-30UG Fiala di plastica 30 μg
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Description
OverviewNative, human des-Arg C5a complement component. Single chain glycopeptide composed of 73 amino acids. Once the C5a glycopeptide has been produced in human plasma or serum, it is rapidly converted to C5a des-Arg upon removal of the C-terminal arginine by the endogenous serum carboxypeptidase N. Unlike the C3a des-Arg peptide, C5a des-Arg retains significant levels of its biological activities. Thus, C5a des-Arg has been shown to exhibit inflammatory cell chemotaxis, smooth muscle contraction, and leukotriene release from guinea pig lung.
Catalogue Number204902
Brand Family Calbiochem®
References
ReferencesWebster, R.O., et al. 1980. Immunopharmacology 1, 201.
McCarthy, K. and Henson, P.M. 1979. J. Immunol. 123, 2511.
Product Information
FormLiquid
FormulationIn 120 mM NaCl, 10 mM HEPES, pH 7.2.
Quality LevelMQ100
Biological Information
Purity≥90% by SDS-PAGE
SourcePrepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Numero di catalogo GTIN
204902-30UG 04055977219869