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230950 Ciglitazone - CAS 74772-77-3 - Calbiochem

A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC₅₀ = 3 µM).

Ciglitazone - CAS 74772-77-3 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: (±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I

Primary Target: Selective PPARγ agonist
230950
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Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
74772-77-3C₁₈H₂₃NO₃S

Products

Numero di catalogoConfezionamento Qtà/conf
230950-5MG Fiala di plastica 5 mg
Description
OverviewA potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).
Catalogue Number230950
Brand Family Calbiochem®
Synonyms(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I
References
ReferencesJha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
Product Information
CAS number74772-77-3
ATP CompetitiveN
FormWhite to tan solid
Hill FormulaC₁₈H₂₃NO₃S
Chemical formulaC₁₈H₂₃NO₃S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetSelective PPARγ agonist
Primary Target IC<sub>50</sub>EC50 = 3 µM as PPARγ agonist
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSXJ5813700
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsStock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
230950-5MG 04055977218312

Documentation

Ciglitazone - CAS 74772-77-3 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Ciglitazone - CAS 74772-77-3 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
230950

Riferimenti bibliografici

Panoramica delle referenze
Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-January-2020 JSW
Synonyms(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I
DescriptionA potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).
FormWhite to tan solid
CAS number74772-77-3
RTECSXJ5813700
Chemical formulaC₁₈H₂₃NO₃S
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (≥ 25 mg/ml) or Ethanol (≥25 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsStock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful
ReferencesJha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.