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235420 Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem

235420
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Tabella delle specifiche principali

CAS #Empirical Formula
169332-60-9C₂₀H₃₀N₄O₁₁

Products

Numero di catalogoConfezionamento Qtà/conf
235420-1MG Bottiglia di vetro 1 mg
235420-5MG Fiala di plastica 5 mg
Description
OverviewA very potent, specific, and reversible inhibitor of caspase-3 (IC50 = 200 pM), caspase-6, caspase-7, caspase-8, and caspase-10.
Catalogue Number235420
Brand Family Calbiochem®
SynonymsCPP32/Apopain Inhibitor, Ac-DEVD-CHO
References
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Nicholson, D.W. 1996. Nature Biotech. 14, 297.
Schlegel, J., et al. 1996. J. Biol. Chem. 271, 1841.
Nicholson, D.W., et al. 1995. Nature 376, 37.
Product Information
CAS number169332-60-9
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₀H₃₀N₄O₁₁
Chemical formulaC₂₀H₃₀N₄O₁₁
ReversibleY
Sold on the basis of peptide contentY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetCapase-3, capase-6, capase-7, capase-8, capase-10
Primary Target IC<sub>50</sub>200 pM against caspase-3
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceAc-Asp-Glu-Val-Asp-CHO
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Numero di catalogo GTIN
235420-1MG 07790788060220
235420-5MG 04055977199697