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205546 Caffeic Acid - CAS 331-39-5 - Calbiochem

A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties.

Caffeic Acid - CAS 331-39-5 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 3,4-Dihydroxycinnamic Acid

Primary Target: 5-lipoxygenase
205546
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Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
331-39-5C₉H₈O₄

Products

Numero di catalogoConfezionamento Qtà/conf
205546-500MG Fiala di plastica 500 mg
Description
OverviewA natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
Catalogue Number205546
Brand Family Calbiochem®
Synonyms3,4-Dihydroxycinnamic Acid
References
ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
Product Information
CAS number331-39-5
ATP CompetitiveN
FormTan crystalline solid
Hill FormulaC₉H₈O₄
Chemical formulaC₉H₈O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target5-lipoxygenase
Primary Target IC<sub>50</sub>3.7 µM against 5-lipoxygenase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGD8950000
Safety Information
R PhraseR: 40

Limited evidence of a carcinogenic effect.
S PhraseS: 36/37

Wear suitable protective clothing and gloves.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
205546-500MG 04055977203134

Documentation

Caffeic Acid - CAS 331-39-5 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Caffeic Acid - CAS 331-39-5 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
205546

Riferimenti bibliografici

Panoramica delle referenze
Yamanaka, N., et al. 1997. FEBS Lett. 405, 186.
Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-April-2008 RFH
Synonyms3,4-Dihydroxycinnamic Acid
DescriptionA cell-permeable natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An effective irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
FormTan crystalline solid
Intert gas (Yes/No) Packaged under inert gas
CAS number331-39-5
RTECSGD8950000
Chemical formulaC₉H₈O₄
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (200 mg/ml) or Ethanol (50 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Carcinogenic / Teratogenic
Merck USA index14, 1635
ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.