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14-719M CaM Kinase IIγ Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, CaM Kinase IIγ, amino acids 1-330, for use in Kinase Assays.

14-719M
250 µg  Also available in 10 μg size (cat#14-719) and in bulk (cat#14-719-K).
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Replacement Information
Description
Catalogue Number14-719M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCaM Kinase IIγ Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, CaM Kinase IIγ, amino acids 1-330
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, CaM Kinase IIγ, amino acids 1-330, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Entrez Gene Number
Entrez Gene SummaryThe product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Six alternatively spliced variants that encode six different isoforms have been characterized to date. Additional alternative splice variants that encode different isoforms have been described, but their full-length nature has not been determined.
Gene Symbol
  • CAMK2G
  • MGC26678
  • CAMKG
  • CAMK-II
  • CAMK
  • FLJ16043
Protein TargetCaMKIIγ
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCAMK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q13555 # CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release.
SIZE: 558 amino acids; 62609 Da
SUBUNIT: CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
SIMILARITY: SwissProt: Q13555 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain.
Molecular Weight41.2kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of 250μM ZIPtide (Catalog # 12-545)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-719) and in bulk (cat#14-719-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
14-719M 04053252441578

Documentation

Prodotti e applicazioni correlate

Alternative Packsize

Numero di catalogo Descrizione
14-719 CaM Kinase IIγ Protein, active, 10 µg

Linee di prodotti

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Categorie

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases