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AG723-KC C-Reactive Protein-KC

AG723-KC
Bulk packaging. Please inquire.  
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Panoramica

Replacement Information
Description
Catalogue NumberAG723-KC
DescriptionC-Reactive Protein-KC
References
Product Information
FormatPurified
PresentationLiquid in 100mM NaCl, 10mM Tris-HCl with 0.1% sodium azide, 2mM Calcium
Quality LevelMQ300
Applications
Key Applications
  • Positive Control
Biological Information
Purity>98% by SDS-PAGE.
SourceHuman pleural fluid, negative for HBsAg, anti-HCV, anti-HIV-1 and anti-HIV-2.
Gene Symbol
  • CRP
  • MGC149895
  • PTX1
  • MGC88244
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P02741 # Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
COFACTOR: Binds 2 calcium ions per subunit.
SIZE: 224 amino acids; 25039 Da
SUBUNIT: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Found in plasma.
SIMILARITY: SwissProt: P02741 ## Belongs to the pentaxin family. & Contains 1 pentaxin domain.
MISCELLANEOUS: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceNo precipitin bands when tested at 2 mg/mL against anti-whole human serum.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material SizeBulk packaging. Please inquire.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
AG723-KC 04053252441660