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182540 Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem

The Aromatase Inhibitor I, also referenced under CAS 331684-05-0, controls the biological activity of Aromatase.

Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone

Primary Target: P450 arom.
182540
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Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
331684-05-0C₁₇H₁₁N₃O₄

Products

Numero di catalogoConfezionamento Qtà/conf
182540-1MG Fiala di plastica 1 mg
Description
OverviewA potent, competitive, nonsteroidal inhibitor of aromatase (P450arom; IC50 = 40 nM for human aromatase). Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit 17α-hydroxylase.
Catalogue Number182540
Brand Family Calbiochem®
Synonyms4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone
References
ReferencesRecanatini, M., et al. 2001. J. Med. Chem. 44, 672.
Product Information
CAS number331684-05-0
ATP CompetitiveY
FormWhite solid
Hill FormulaC₁₇H₁₁N₃O₄
Chemical formulaC₁₇H₁₁N₃O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetP450 arom.
Primary Target IC<sub>50</sub>40 nM against P450arom
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
182540-1MG 04055977205091

Documentation

Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
182540

Riferimenti bibliografici

Panoramica delle referenze
Recanatini, M., et al. 2001. J. Med. Chem. 44, 672.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-April-2011 RFH
Synonyms4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone
DescriptionA potent, selective, nonsteroidal, competitive inhibitor of aromatase (P450arom) (IC50 = 40 nM for human aromatase) Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit human 17α-hydroxylase (P450 17) (4% inhibition at 2.5 µM).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number331684-05-0
Chemical formulaC₁₇H₁₁N₃O₄
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesRecanatini, M., et al. 2001. J. Med. Chem. 44, 672.