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07-442-AF647 Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 647 Conjugate

07-442-AF647
100 µL  
Purchase on Sigma-Aldrich

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Panoramica

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Offerte speciali

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Species ReactivityKey ApplicationsHostFormatAntibody Type
HICCRbAlexaFluor®647Polyclonal Antibody
Description
Catalogue Number07-442-AF647
DescriptionAnti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 647 Conjugate
Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
References
Product Information
FormatAlexaFluor®647
PresentationPurified rabbit conjugate in buffer containing PBS, 15 mg/mL BSA, and 0.1 % Sodium Azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 647 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys9).
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenLinear peptide corresponding to Histone H3 trimethylated at Lys9.
Concentration0.5 mg/mL
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Mouse, Rat, and Chicken based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~17 kDa observed. Refer to Cat. No. 07-442 for observed molecular weight information.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvalutated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys9) in HeLa cells.

Alexa Fluor® is a registered trademark of Life Technologies®.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
07-442-AF647 04053252976261