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MABC531 Anti-Somatotropin/GH1 Antibody, clone 1H1.1

MABC531
100 μg  
Purchase on Sigma-Aldrich

Offerte speciali

Panoramica

Replacement Information

Offerte speciali

Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC531
DescriptionAnti-Somatotropin/GH1 Antibody, clone 1H1.1
Alternate Names
  • Somatotropin
  • Growth hormone
  • GH
  • GH-N
  • Growth hormone 1
  • Pituitary growth hormone
  • -Somatotropin/GH1
Background InformationSomatotropin (UniProt P01241; also known as GH, GH-N, Growth hormone 1, hGH-N, Pituitary growth hormone) is encoded by the GH1 (also known as GH, GHN, IGHD1B) gene (Gene ID 8856) in human. Somatotropin is a peptide hormone that plays an important role in growth control by inducing IGF-1 secretion in liver and other tissues. It stimulates myoblast differentiation and proliferation, as well as amino acids uptake and protein synthesis in muscle and other tissues. Acromegaly is a rare endocrine syndrome caused by a GH-secreting pituitary adenoma. Acromegaly may also be rarely associated with a hypothalamic or an ectopic GH-releasing hormone-producing tumor.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Somatotropin/GH1 Antibody, clone 1H1.1 is an antibody against Somatotropin/GH1 for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Somatotropin/GH1.
Clone1H1.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityExpected to react with isoforms 1, 3, and 4. Reactivity to isoforms 2 and 5 have not been tested.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • GH1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~25 kDa observed. This protein has several isoforms from ~20-25 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human pituitary tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Somatotropin/GH1 in 10 µg of human pituitary tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
MABC531 04055977170665

Documentation

Anti-Somatotropin/GH1 Antibody, clone 1H1.1 MSDS

Titolo

Scheda di sicurezza (MSDS) 

Anti-Somatotropin/GH1 Antibody, clone 1H1.1 Certificati d'Analisi

TitoloNumero di lotto
Anti-Somatotropin/GH1, clone 1H1.1 3948896 3948896
Anti-Somatotropin/GH1, clone 1H1.1 - 3477806 3477806
Anti-Somatotropin/GH1, clone 1H1.1 -Q2573148 Q2573148

Informazioni tecniche

Titolo
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White Paper: Further considerations of antibody validation and usage.