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ABC244 Anti-PATE1 Antibody

This Anti-PATE1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PATE1.

Anti-PATE1 Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: PATE1, PATE UniProt Number: Q8WXA2
ABC244
100 µL  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC244
DescriptionAnti-PATE1 Antibody
Alternate Names
  • Prostate and testis expressed protein 1
Background InformationPATE1 is a secreted protein that is expressed exclusively in the prostate and testis and is up regulated in the prostate epithelial cells during cancer. Because of the extreme specificity of PATE1 expression it makes it a potential target for immunotherapy in prostate cancer. PATE1 is the founding member of new syntenic loci in humans and mice that encode secreted proteins that have 10 cysteine residues. The PATE family has three-fingered protein/Ly-6/urokinase-type plasminogen activator receptor (uPAR) domains that shape three-fingered proteins (TFPs). Additional members include PATE-M, PATE-DJ, and PATE-B that are also expressed in prostate and testis and sperm. Related proteins, PATE-P and PATE-Q are expressed only in placenta. Research indicates that PATE proteins may have something to do with fertility and recent research showed that addition PATE-like genes were expressed in neuron-rich tissues and thus may have a role in neurological function or transmission.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-PATE1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PATE1.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected PATE1 in human testis and human hyperplastic prostate tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human PATE1.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Rat
Species Reactivity NoteHuman, Rat. Predicted to react with mouse based on 70% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PATE1
  • PATE
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~14 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat testis tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected PATE1 in 10 µg of rat testis tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
ABC244 04053252986406