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ABN643 Anti-LRRTM2 Antibody

Anti-LRRTM2 Antibody detects level of LRRTM2 & has been published & validated for use in LRRTM2.

Anti-LRRTM2 Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: LRRTM2, KIAA0416, LRRN2 UniProt Number: O43300
ABN643
100 µg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN643
DescriptionAnti-LRRTM2 Antibody
Alternate Names
  • Leucine-rich repeat transmembrane neuronal protein 2
  • Leucine-rich repeat neuronal 2 protein
  • LRRTM2
Background InformationLeucine-rich repeat transmembrane neuronal protein 2, also known as Leucine-rich repeat neuronal 2 protein, and encoded by the gene name LRRTM2 or LRRN2, is involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-LRRTM2 Antibody detects level of LRRTM2 & has been published & validated for use in LRRTM2.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected LRRTM2 in human brain tissue.
Biological Information
ImmunogenKLH-conjugated synthetic peptide corresponding to the cytoplasmic domain of human LRRTM2.
Epitopecytoplasmic domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • LRRTM2
  • KIAA0416
  • LRRN2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~65 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in SK-N-SH cell lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected LRRTM2 in SK-N-SH cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
ABN643 04053252946653