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MABC563 Anti-Kallikrein 2/KLK2 Antibody, clone 4F2.3

Anti-Kallikrein 2/KLK2 Antibody, clone 4F2.3 is an antibody against Kallikrein 2/KLK2 for use in Western Blotting and Immunohistochemistry.

Anti-Kallikrein 2/KLK2 Antibody, clone 4F2.3 : MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: KLK2 UniProt Number: P20151
MABC563
100 µg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC563
DescriptionAnti-Kallikrein 2/KLK2 Antibody, clone 4F2.3
Alternate Names
  • Kallikrein 2
  • KLK2
  • Glandular kallikrein-1
  • hGK-1
  • Tissue kallikrein-2
Background InformationKallikrein-2, also known as Glandular kallikrein-1 (hGK-1) or Tissue kallikrein-2, is encoded by the KLK2 gene. Kallikrein-2 is a serine protease produced by secretory epithelial cells in the prostate. Kallikrein-2 cleaves Met-Lys and Arg-Ser amide linkages in kininogen to release Lys-bradykinin. It is also known to activate the proforms of prostate-specific antigen (PSA) and urokinase type plasminogen activator (uPA), as well as inactivate plasminogen activator inhibitor-1 (PAI-1). both PSA and Kallikrein-2 are used as prostate cancer markers.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Kallikrein 2/KLK2 Antibody, clone 4F2.3 is an antibody against Kallikrein 2/KLK2 for use in Western Blotting and Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Kallikrein 2/KLK2 in human prostate tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Kallikrein 2/KLK2.
Clone4F2.3
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • KLK2
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~30 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in LNCaP cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Kallikrein 2/KLK2 in 10 µg of LNCaP cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
MABC563 04055977159295