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AB9433-I Anti-GLP1R Antibody

This Anti-GLP1R Antibody is validated for use in Immunohistochemistry (Paraffin) for the detection of GLP1R.

Anti-GLP1R Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Metabolism, Signaling Research Sub-Category: Lipid Metabolism & Weight Regulation, Lipid Signaling Gene Symbol: GLP1R UniProt Number: P43220
AB9433-I
100 µg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MIH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9433-I
ReplacesAB9433
DescriptionAnti-GLP1R Antibody
Alternate Names
  • GLP-1R
  • GLP-1 Receptor
  • GLP1-R
  • GLP1R,GLP-1-R
Background InformationGlucagon-Like Peptide 1 Receptor (GLP-1R) is the receptor for glucagon-like peptide 1 and is expressed in the pancreatic beta cells. Ligand binding activates adenyl-cyclase activity which results in increased insulin synthesis and release. GLP-1R is also expressed in the brain where it functions in the control of appetite, memory and learning. GLP-1R also has neuroprotective functions which may be beneficial in diseases such as Huntington's disease, and drugs that are GLP-1R agonists (acts like natural ligand to activate the receptor) such as Exendin-4 are being examined as potential therapies for the disease as well as diabetes and other memory and metabolic disorders.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit Polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-GLP1R Antibody is validated for use in Immunohistochemistry (Paraffin) for the detection of GLP1R.
Key Applications
  • Immunohistochemistry (Paraffin)
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the extracellular domain of Human Glucagon-Like Peptide 1 Receptor.
Epitopeextracellular domain, near N-Terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • GLP1R
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight53 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry (Paraffin) on endocrine cells in human pancreas.

Immunohistochemistry Analysis: 2 ug/ml this antibody showed cytoplasmic staining of subsets of endocrine cells in islets of Langerhans in human pancreas.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
AB9433-I 04055977052824