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04-968 Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2

Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 detects level of Folr4 (Folate receptor 4) & has been published & validated for use in WB.

Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Inflammation & Immunology Research Sub-Category: Inflammation & Autoimmune Mechanisms Gene Symbol: Folbp3, Folr4, FR-delta UniProt Number: A6ND01
04-968
100 µg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWBMPurifiedMonoclonal Antibody
Description
Catalogue Number04-968
DescriptionAnti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2
Alternate Names
  • folate receptor 4 (delta) homolog (mouse)
  • folate receptor 4 (delta) homolog
  • Folate receptor 4
Background InformationFolates are necessary and critical components in the synthesis of proteins and nucleic acids, and have putative roles in the development of both the spinal canal and brain in the early stages of pregnancy (Yamaguchi, 2007). Folate receptor 4 (Folr4) is a recently discovered cell surface receptor for folic acid on T regulatory cells (Tregs). Studies have shown that Folr4 has an integral role in the maintenance of Treg cell function (Arase, 2009). Expression of Folr4 in Tregs is notably high, making it an opportune marker for the study of Treg cells. When studied in conjunction with CD4 and CD25, Folr4 also provides researchers with a marker to distinguish between Tregs and other T cells (Chai, 2008). Tregs are of interest in therapeutic, drug research due to their ability to actively suppress immune responses.
References
Product Information
FormatPurified
Control
  • Human thymus tissue lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 detects level of Folr4 (Folate receptor 4) & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern Blot (SNAP ID) Analysis: 1 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Folate receptor 4 (Folr4).
EpitopeUnknown
Clone5E12.2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody recognizes Folate receptor 4 (Folr4).
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Folbp3
  • Folr4
  • FR-delta
Purification MethodProtein G Purified
UniProt Number
UniProt SummarySUBCELLULAR LOCATION: Secreted Potential.

PTM: Eight disulfide bonds are present Potential.

SEQUENCE SIMILARITIES: Belongs to the folate receptor family.
Molecular Weight~26 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in human thymus tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.
A previous lot was shown to detect Folate Receptor 4 in mouse thymus tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
04-968 04053252410932

Documentation

Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 MSDS

Titolo

Scheda di sicurezza (MSDS) 

Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 Certificati d'Analisi

TitoloNumero di lotto
Anti-Folr4 (Folate receptor 4), clone 5E12.2 - 2376670 2376670
Anti-Folr4 (Folate receptor 4), -2669849 2669849
Anti-Folr4 (Folate receptor 4), -2723534 2723534
Anti-Folr4 (Folate receptor 4), -2726180 2726180
Anti-Folr4 (Folate receptor 4), -2732607 2732607
Anti-Folr4 (Folate receptor 4), -2766381 2766381
Anti-Folr4 (Folate receptor 4), clone 5E12.2 PRODUCT
Anti-Folr4 (Folate receptor 4), clone 5E12.2 - 3593756 3593756
Anti-Folr4 (Folate receptor 4), clone 5E12.2 - NRG1721908 NRG1721908
Anti-Folr4 (Folate receptor 4), clone 5E12.2 Monoclonal Antibody 2869699
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