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ABT259 Anti-Fibrinogen gamma chain Antibody

Anti-Fibrinogen gamma chain Antibody is an antibody against Fibrinogen gamma chain for use in Immunohistochemistry and Immunocytochemistry.

Anti-Fibrinogen gamma chain Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: Fgg UniProt Number: Q8VCM7
ABT259
100 µg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT259
DescriptionAnti-Fibrinogen gamma chain Antibody
Alternate Names
  • Fibrinogen gamma chain
Background InformationThe gamma component of fibrinogen is a glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Various cleavage fragments of fibrinogen and fibrin also regulate cell adhesion, vasoconstricting, chemotaxis, and mitosis. Disorders caused by gamma chain mutations include dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants, the common gammaA and the less abundant gamma'.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Fibrinogen gamma chain Antibody is an antibody against Fibrinogen gamma chain for use in Immunohistochemistry and Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Fibrinogen gamma chain in mouse kidney and mouse liver tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the fibrinogen C-terminal domain of mouse Fibrinogen gamma chain.
EpitopeFibrinogen C-terminal Domain
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Mouse
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Fgg
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~55 kDa observed. The calculated molecular weight is 49 kDa, however Fibrinogen gamma chain has been shown as a ~55 kDa band due to glycosylation (Nickerson, J.M., et al. (1981). Biochemistry. 20:2818-2821).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse liver tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Fibrinogen gamma chain in 10 µg of mouse liver tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
ABT259 04055977136326

Documentation

Anti-Fibrinogen gamma chain Antibody Certificati d'Analisi

TitoloNumero di lotto
Anti-Fibrinogen gamma chain - 3249413 3249413
Anti-Fibrinogen gamma chain - 3397943 3397943
Anti-Fibrinogen gamma chain -Q2556980 Q2556980

Riferimenti bibliografici

Panoramica dei riferimenti bibliograficiCodice d'identificazione nel Pub Med
Biochemistry
Nickerson, JM; Fuller, GM
Biochemistry  20  2818-21  1981

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Informazioni tecniche

Titolo
White Paper: Further considerations of antibody validation and usage.