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ABE1000 Anti-FOXM1 Antibody

Anti-FOXM1 Antibody is an antibody against FOXM1 for use in western blotting, IHC & IP.

Anti-FOXM1 Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: FOXM1, FKHL16, HFH11, MPP2, WIN UniProt Number: Q08050
ABE1000
100 µg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHC, IPRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE1000
DescriptionAnti-FOXM1 Antibody
Alternate Names
  • Forkhead box protein M1
  • Forkhead-related protein FKHL16
  • Hepatocyte nuclear factor 3 forkhead homolog 11
  • HFH-11
  • HNF-3/fork-head homolog 11
  • M-phase phosphoprotein 2
  • MPM-2 reactive phosphoprotein 2
  • Transcription factor Trident
  • Winged-helix factor from INS-1 cells
Background InformationForkhead box M1 (FOXM1), also named HNF-3, HFH-11 or Trident, belongs to a superfamily of Fox transcription factors. FOXM1 is strongly associated with cell proliferation and plays an important role in cell cycle progression by regulating both G1/S and G2/M phases. FOXM1 is also involved in DNA damage repair, angiogenesis, apoptosis, and tissue regeneration. Recently, crucial roles of this transcription factor were found in the development and progression of many cancers including colorectal, lung, prostate, liver and breast cancer. FOXM1 levels are significantly higher and associated with tumor grade in most human tumors, rendering it a potential target of cancer diagnosis and therapies.
References
Product Information
FormatAffinity Purified
HS Code3002 15 90
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-FOXM1 Antibody is an antibody against FOXM1 for use in western blotting, IHC & IP.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunoprecipitation
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FOXM1 in human testis tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to a region near the C-terminus of human FOXM1.
EpitopeNear C-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody is expected to detect three known isoforms of FOXM1 based upon immunogen design.
Species Reactivity
  • Human
  • Mouse
Species Reactivity NoteHuman and Mouse. Predicted to react with Primate, Monkey, Chimpanzee and Canine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FOXM1
  • FKHL16
  • HFH11
  • MPP2
  • WIN
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~88 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human thymus tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected FOXM1 in 10 µg of human thymus tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
ABE1000 04053252961083