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ABC501 Anti-EDG3 Antibody

Anti-EDG3 Antibody is an antibody against EDG3 for use in Western Blotting and Immunohistochemistry.

Anti-EDG3 Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: S1PR3, EDG3 UniProt Number: Q99500
ABC501
100 µg  
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Panoramica

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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC501
DescriptionAnti-EDG3 Antibody
Alternate Names
  • EDG3
  • Sphingosine 1-phosphate receptor 3
  • S1P receptor 3
  • S1P3
  • Endothelial differentiation G-protein coupled receptor 3
  • Sphingosine 1-phosphate receptor Edg-3
  • S1P receptor Edg-3
Background InformationEDG3, also known as Sphingosine 1-phosphate receptor 3, S1P receptor 3 or S1P3 or Endothelial differentiation G-protein coupled receptor 3 or Sphingosine 1-phosphate receptor Edg-3 or S1P receptor Edg-3, and encoded by the gene name S1PR3 or EDG3, EDG3 is a member of the EDG family of receptors, which are G protein-coupled receptors. It has been identified as a functional receptor for sphingosine 1-phosphate (S1P) and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-EDG3 Antibody is an antibody against EDG3 for use in Western Blotting and Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected EDG3 in human kidney and human liver tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the C-terminus of human EDG3.
EpitopeC-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Feline based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • S1PR3
  • EDG3
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~52 kDa observed. The calculated molecular weight of this protein is 42 kDa, but can be observed at ~52 kDa due to high glycosylation (Magrassi, L., et al. (2010). Cancer Letters. 290(1):36-42). Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Caco-2 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected EDG3 in 10 µg of Caco-2 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
ABC501 04055977151725

Documentation

Anti-EDG3 Antibody Certificati d'Analisi

TitoloNumero di lotto
Anti-EDG3 - 3397944 3397944
Anti-EDG3 -Q2559136 Q2559136

Riferimenti bibliografici

Panoramica dei riferimenti bibliograficiCodice d'identificazione nel Pub Med
Cancer letters
Magrassi, L; Marziliano, N; Inzani, F; Cassini, P; Chiaranda, I; Skrap, M; Pizzolito, S; Arienta, C; Arbustini, E
Cancer letters  290  36-42  2009

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Brochure

Titolo
NPI Flyer- Epigenetics and Nuclear Function Feature

Informazioni tecniche

Titolo
White Paper: Further considerations of antibody validation and usage.