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MABD45 Anti-DDPIV/CD26 Antibody, clone 9F1.2

MABD45
100 μg  
Purchase on Sigma-Aldrich

Offerte speciali

Panoramica

Replacement Information

Offerte speciali

Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABD45
DescriptionAnti-DDPIV/CD26 Antibody, clone 9F1.2
Alternate Names
  • Dipeptidyl peptidase 4
  • ADABP
  • Adenosine deaminase complexing protein 2
  • ADCP-2
  • Dipeptidyl peptidase IV
  • DPP IV
  • T-cell activation antigen CD26
  • TP103
  • CD26
  • Dipeptidyl peptidase 4 membrane form
  • Dipeptidyl peptidase IV membrane form
  • Dipeptidyl peptidase 4 soluble form
  • Dipeptidyl peptidase IV soluble form
  • DDPIV/CD26
Background InformationDipeptidyl peptidase 4 (EC 3.4.14.5; UniProt P27487; also known as ADABP, ADCP-2, Adenosine deaminase complexing protein 2, DPP IV, T-cell activation antigen CD26, Adenosine deaminase complexing protein 2, Dipeptidyl peptidase 4, Dipeptidylpeptidase IV, TP103) is encoded by the DPP4 (also known as CD26, ADCP2) gene (Gene ID 1803) in human. DPPIV is a homodimeric serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. It is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes. Also, DPPIV acts as a functional receptor for the newly discovered Middle East respiratory syndrome (MERS) coronavirus.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-DDPIV/CD26 Antibody, clone 9F1.2 is validated for use in Western Blotting for the detection of DDPIV/CD26.
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the extracellular domain of human DDPIV/CD26.
Epitopeextracellular domain
Clone9F1.2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityReacts with both membrane-bound (MDPP) and soluble (SDPP) forms.
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • DPP4
  • ADCP2
  • CD26
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~100 kDa observed. Due to glycosylation, target band appears larger than the calculated molecular weight of 88.3 (MDPP) & 84.4 (SDPP) kDa. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in PC3 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected DDPIV/CD26 in 10 µg of PC3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
MABD45 04055977182576

Documentation

Anti-DDPIV/CD26 Antibody, clone 9F1.2 MSDS

Titolo

Scheda di sicurezza (MSDS) 

Anti-DDPIV/CD26 Antibody, clone 9F1.2 Certificati d'Analisi

TitoloNumero di lotto
Anti-DDPIV/CD26, clone 9F1.2 - 3763307 3763307
Anti-DDPIV/CD26, clone 9F1.2 - 4158372 4158372
Anti-DDPIV/CD26, clone 9F1.2 -Q2589912 Q2589912

Informazioni tecniche

Titolo
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White Paper: Further considerations of antibody validation and usage.