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ABT123 Anti-Collagen Type I Antibody

ABT123
100 µL  
Purchase on Sigma-Aldrich

Offerte speciali

Panoramica

Replacement Information

Offerte speciali

Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RWB, IH(P), ELISARbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT123
ReplacesAB755P
DescriptionAnti-Collagen Type I Antibody
Alternate Names
  • Collagen alpha-1(I) chain
  • Alpha-1 type I collagen
Background InformationCollagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
References
Product Information
FormatAffinity Purified
Control
  • Rat skin tissue
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Collagen Type I using this Anti-Collagen Type I Antibody validated for use in Western Blotting, IHC(P), ELISA.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
  • ELISA
Application NotesSpecificity ELISA Analysis: A representative lot detected mouse and rat collagen but not human collagen in ELISA.

Western Blot Analysis: A 1:2,000 dilution from a representative lot detected Collagen Type 1 on 10 µg of rat skin tissue lysate.
Biological Information
ImmunogenRat tail collagen
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • COL1A1
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight130 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in rat skin tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Collagen Type 1 in rat skin tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
ABT123 04053252647918

Documentation

Anti-Collagen Type I Antibody MSDS

Titolo

Scheda di sicurezza (MSDS) 

Anti-Collagen Type I Antibody Certificati d'Analisi

TitoloNumero di lotto
Anti-Collagen Type I 3072327
Anti-Collagen Type I - 2388363 2388363
Anti-Collagen Type I - 2449235 2449235
Anti-Collagen Type I - 2465283 2465283
Anti-Collagen Type I - 2199190 2199190
Anti-Collagen Type I - 2297296 2297296
Anti-Collagen Type I - 3293728 3293728
Anti-Collagen Type I - 3327702 3327702
Anti-Collagen Type I - 3494040 3494040
Anti-Collagen Type I - 3539821 3539821

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Categorie

Life Science Research > Antibodies and Assays > Primary Antibodies