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ABC151 Anti-Annexin A1, Antibody

Anti-Annexin A1 is an antibody targeting the Annexin A1 protein, validated for use in WB & IHC.

Anti-Annexin A1, Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: ANXA1, ANX1, LPC1 UniProt Number: P04083
ABC151
100 µg  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, R, Porcine, Chp, BWB, IHCRbPurifiedPolyclonal Antibody
Description
Catalogue NumberABC151
DescriptionAnti-Annexin A1, Antibody
Alternate Names
  • Annexin A1
  • Annexin I
  • Annexin-1
  • Calpactin II
  • Calpactin-2
  • Chromobindin-9
  • Lipocortin I
  • Phospholipase A2 inhibitory protein
  • p35
Background InformationAnnexin A1 (ANXA1) is a calcium and phospholipid binding protein almost entirely restricted to microglia in the CNS. During the peripheral inflammatory response, Annexin A1 is instrumental in the phagocytosis of apoptotic leukocytes. Annexin A1 restores the ability of microglia to differentiate between apoptotic and non-apoptotic cells during inflammatory activation. Current research is geared towards using Annexin A1 as a therapeutic target in neuroinflammation. Annexin A1 has also been shown to be influential in cancer development and proliferation.
References
Product Information
FormatPurified
Control
  • L6 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Annexin A1 is an antibody targeting the Annexin A1 protein, validated for use in WB & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blot Analysis: 2.0 µg/mL from a representative lot detected Annexin A1 in 10 µg of C2C12, HUVEC, and NIH/3T3 cell lysate.
Immunohistochemistry Analysis: 1:500 dilution from a representative lot detected Annexin A1 in human lung tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human Annexin A1.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of Annexin A1
Species Reactivity
  • Human
  • Mouse
  • Rat
  • Porcine
  • Chimpanzee
  • Bovine
Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Porcine, Chimpanzee, and Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ANXA1
  • ANX1
  • LPC1
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~38 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in L6 cell lysate.

Western Blot Analysis: 2.0 µg/mL of this antibody detected Annexin A1 in 10 µg of L6 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
ABC151 04053252830815